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Bestatin HCl, 5 MG

Price$ 53.25
  • SKU: B-1075-5MG
  • Pack Size: 5 MG
Quantity
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Ubenimex hydrochloride; N-[(2S,3R)-3-Amino-2-hydroxy4-phenylbutyryl]-Lleucinehydrochloride

65391-42-6

344.8

C16H24N2O4 • HCl

Water

-20°C


Bestatin hydrochloride is a metalloprotease inhibitor of aminopeptidase, aminopeptidase B, aminopeptidase M (CD13), and leucine aminopeptidase (LAP3) derived from Streptomyces olivoreticuli.

The inhibition of these proteins is due to apoptosis induction in oncogenic cells. Bestatin displays efficacy in anticancer chemotherapeutic, immunomodulatory, and analgesic activities


Applications:

  • Treatment of acute promyelocytic leukemia
  • Intensified the antinociceptive effects of low-dose of NA3
  • Enhances proliferation of bone marrow macrophage progenitor cells
  • Amplifies formation of CFU-GM colonies
  • Efficacy in lung cancer treatments

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.
  • Appearance: white Powder
  • Purity: ≥ 99.00 %
  • Elemental Analysis (C): 54.6 - 56.9 %
  • Elemental Analysis (H): Report %
  • Elemental Analysis (N): 8.0 - 8.3 %
  • Elemental Analysis (Cl): 10.0 - 10.6 %
  • Water (KF): ≤ 6 %
  • Solubility: 10 mg/ml in water, upto 20 mg/ml in HCL, up to 5 mg/ml in Methanol
  • Statement-1: Stable at -20 °C if desiccated and properly stored for at least 24 months. Short term 2-8°C. Ship with blue ice.

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